I flew around 20 weeks and then again at 25 weeks, and it wasnt so bad for me.... but I hate flying anyways because I find it so uncomfortable to be cooped up for so long. I wuold say for sure get an aisle seat (I had to pee like 4 times each way, and i felt bad for the lady on the aisle). If you get nauseous, maybe try ginger candies or tea if you can get it in. If you want to try to sleep, a neck pillow thing or a blanket... and a good book!! Colorado to TX shouldnt take too long, right? My biggest dread about flying is all the germs, so personally i focus on just beefing up my vit c beforehand, lots of water, and wash my hands often!
Have a great trip... it's for your baby shower, right!?